Nurse Betty

Morgan Freeman

Charlie

Renée Zellweger

Betty

Chris Rock

Wesley

Greg Kinnear

Dr. David Ravell

Aaron Eckhart

Del

Tia Texada

Rosa

Crispin Glover

Roy

Pruitt Taylor Vince

Ballard

Allison Janney

Lyla

Kathleen Wilhoite

Sue Ann

Elizabeth Mitchell

Chloe

Susan Barnes

Darlene

Harriet Sansom Harris

Ellen

Sung-Hi Lee

Jasmine

Laird Macintosh

Dr. Lonnie Walsh